منابع مشابه
Information theory in molecular biology
This article introduces the physics of information in the context of molecular biology and genomics. Entropy and information, the two central concepts of Shannon’s theory of information and communication, are often confused with each other but play transparent roles when applied to statistical ensembles (i.e., identically prepared sets) of symbolic sequences. Such an approach can distinguish be...
متن کاملInformation and communication theory in molecular biology
The DNA sequencing efforts of the past years together with rapid progress in sequencing technology have generated a huge amount of sequence data available in public molecular databases. This recent development makes it statistically feasible to apply universal concepts from Shannon’s information theory to problems in molecular biology, e.g to use mutual information for gene mapping and phylogen...
متن کاملShannon Information Theory and Molecular Biology
The role and the contribution of Shannon Information Theory to the development of Molecular Biology has been the object of stimulating debates during the last thirty years. This seems to be connected with some semantic charms associated with the use of the word “information” in the biological context. Furthermore information itself, if viewed in a broader perspective, is far from being complete...
متن کامل1 Some Lessons for Molecular Biology from Information Theory
Applying information theory to molecular biology problems clarifies many issues. The topics addressed are: how there can be precision in molecular interactions, how much pattern is stored in the DNA for genetic control systems, and the roles of theory violations, instrumentation, and models in science. This paper is a short review of a few of the lessons I’ve learned from applying Shannon’s inf...
متن کاملInformation extraction in molecular biology
Information extraction has become a very active field in bioinformatics recently and a number of interesting papers have been published. Most of the efforts have been concentrated on a few specific problems, such as the detection of protein-protein interactions and the analysis of DNA expression arrays, although it is obvious that there are many other interesting areas of potential application ...
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ژورنال
عنوان ژورنال: Physics of Life Reviews
سال: 2004
ISSN: 1571-0645
DOI: 10.1016/j.plrev.2004.01.002